Update: Viibryd, NSAIDs + SSRIs = Trouble

Viibryd’s going to be late. Taking aspirin, ibuprofen, or naproxen with Zoloft, Prozac, or Celexa increases the risk for an upper GI bleed. You need to know!

Here are two important updates…


Some time ago I ran a piece on the new selective serotonin reuptake inhibitor (SSRI) antidepressant, vilazodone (Viibryd). In the article I mentioned the target availability date was no later than May 31 of this year.

My sources tell me the on-the-shelf date has been pushed back to the end of the summer.

Will keep you posted as I hear more. Here’s a link to the original article.

***I’ve decided to maintain an ongoing journal of chipur readers’ experiences with Viibryd. Click here and you’re there!

NSAIDs + SSRIs = Trouble

I published an article about a week ago citing research that NSAIDs (aspirin, ibuprofen, naproxen, etc.) reduce the effects of the selective serotonin reuptake inhibitor (SSRI) antidepressants ( Zoloft, Prozac, Celexa, etc. – and now Viibryd).

Seems there’s a whole lot more to the story.

Research is warning us that the interaction of an NSAID and an SSRI increases the risk of an upper GI bleed six-fold.

But wait, there’s more!

Taking an SSRI alone more than doubles the risk of an upper GI bleed. An NSAID alone increases the risk by three-fold.

Wild thing is, the NSAID/SSRI bleed dynamic doesn’t seem to be attributable to 2x the meds. Reportedly, there’s an unexpected chemistry involved.

Here’s a link to the original NSAID/SSRI piece.

The Wrap

So there you have it, very important updates on topics featured on chipur. You need to know these things, and I’ll make it my business to get the info to you.

Mission accomplished (for now)!